Pirfenidone

Pirfenidone is an orally administered drug with antifibrotic, anti-inflammatory and antioxidant effects that was approved in Europe in 2011 and in USA in 2014 for the treatment of lung disease called idiopathic pulmonary fibrosis (IPF).
Pirfenidone is an agent with the ability to decrease TGF-β1, TNFα, TNFβ, PDGF and COL1A1 expression, which is highly related to prevent or remove excessive deposition of scar tissue in several organs.

Molecular structure:

• Molecular formula: C₁₂H₁₁NO
• Molecular weight: 185.2
• CAS Number: 53179-13-8
• Application: to treat idiopathic pulmonary fibrosis.
• Specification: As per IP/BP/EP/IHS

IUPAC Name/ACD Name:
5-Methyl-1-phenyl-2(1H)-pyridinone

Chemical Name:
5-methyl-1-phenylpyridin-2-one