Rivaroxaban was the first orally dosed, direct Factor Xa inhibitor, a small-molecule oxazolidinone derivative. It binds directly and reversibly to Factor Xa via the S1 and S4 pockets.
Molecular structure:
Molecular formula: C19H18CIN3O5S
Molecular weight: 435.88
CAS Number: 366789-02-8
Application: Used to treat venous thromboembolism (VTE), deep vein thrombosis (DVT) and pulmonary embolism (PE).